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Typically the character may be: becoming a nun; reacting to the effects of chemotherapy; or undergoing some other sort of cathartic transformation. A very few even agreed to be filmed shaving their own heads in character.
Sometimes it’s for that extra bit of authenticity; sometimes it’s for the money; sometimes it’s for the publicity that might revive a flagging career or kick-start a new one. I don’t understand why most of the actresses who have appeared bald in movies agreed to have their heads shaved: why they would agree to it being filmed and how they could have the confidence that they could remain in character throughout the process is beyond me.